Clinical innovation

在临床和其他领域开拓与患者和试验团队接触的新方法

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What is clinical innovation?


临床试验是提供下一波改变生活的药物的基石. However, healthcare environments are becoming increasingly complex, creating new challenges for clinical trial research. Recently, the upsurge in digital healthcare has catalysed and accelerated changes in clinical trial recruitment and participation, adding further complexity. Furthermore, the transition towards next-generation therapeutics 是否有必要改变临床试验的设计和交付. To meet these demands for clinical innovation, we are pioneering new approaches to how we engage with patients, trial teams and healthcare providers, in the clinic and beyond.




Clinical innovation means we are constantly thinking about how we can design and deliver patient-centric clinical trials that improve the experience of patients and site teams, and how we can use data, digital and AI to improve patient outcomes and health equity.

Natalie Fishburn VP and Head of Clinical Operations, BioPharmaceuticals R&D, AstraZeneca

Learn how we are delivering the next wave of life-changing medicines to the patients who need them most through clinical innovation


Clinical trial transparency

澳门第一赌城在线娱乐长期致力于公开澳门第一赌城在线娱乐的临床研究信息. 澳门第一赌城在线娱乐相信对澳门第一赌城在线娱乐的研发保持透明, including our clinical trials, is serving the best interests of patients, their relatives, caregivers, healthcare professionals, researchers and the public.

The aim of our clinical trial website is to increase knowledge and awareness of clinical trials including what it means to participate and to increase access to relevant clinical trials for patients.




使用数据和数字健康解决方案来改善体验和患者治疗效果


We have the opportunity to integrate digital health solutions 通过临床试验,帮助患者获得更好的健康结果. Digital health technologies have the potential to enable a broader group of people to participate and reduce patients’ need to travel to the clinic.

数字技术也使澳门第一赌城在线娱乐能够使用病人在家就能使用的设备来收集数据. 这使医疗保健提供者能够实时监测症状和生命体征, giving clinicians and study teams a better understanding of how an investigational medicine impacts a disease and how it interacts with an individual’s overall health and quality of life. By leveraging digital technology, 澳门第一赌城在线娱乐还减少了为最需要的患者开发改变生活的药物所需的时间.





探索在澳门第一赌城在线娱乐的临床试验中创新使用数据和数字技术的例子





The opportunity for digital health to improve human health and transform patient outcomes is starting to be realised. We are at the forefront of this healthcare revolution, powered by scientific evidence, digital, longitudinal multiomics health data, and AI.




Designing and delivering patient-centric clinical trials


Clinical trials are necessary to drive innovation, 然而,只有一小部分符合条件的患者选择或能够参加试验. To enable more patients to participate, we are focusing on making them more accessible, providing simpler information and designing our trials so they are easier and more flexible for patients to fit around their routine care.



Learning from the patient experience

澳门第一赌城在线娱乐与患者和护理人员合作,让他们的声音进入澳门第一赌城在线娱乐的试验. For patients with rare diseases, Alexion’s Rare Disease Patient Friction Coefficient assesses the burden of clinical trials on patients and their families and allows us to utilise these insights to inform and improve our trial designs and protocols. Across other disease areas, we have surveyed more than 1,400 patients about the burdens they face during clinical trials. When designing new studies, we use Merlin, a tool that proactively calculates a score to help our study teams evaluate how burdensome a trial might be for patients. Based on these data, 澳门第一赌城在线娱乐的研究团队可以做出明智的决定,以减少试验中这些潜在的负担.


Designing patient-centric trial endpoints

Designing better trial endpoints is one way to support clinical decision-making and capture the whole disease burden and trial journey of patients. A trial endpoint is an event or outcome that can be objectively measured to determine whether the intervention or treatment being studied is beneficial. For several of our asthma and COPD clinical trials, 澳门第一赌城在线娱乐已经开发了新的复合终点,帮助澳门第一赌城在线娱乐减少临床试验的规模和持续时间. Moreover, we piloted the use of at-home spirometry measurements and virtual coaching to enable the remote collection of data for this endpoint, 将亲自就诊的需求减少50%,并减少患者的旅行需求.


Delivering patient-centred and innovative clinical trial designs

Where possible, 澳门第一赌城在线娱乐正在引入创新的临床试验设计,可以减轻患者的负担, accelerate timelines and increase efficiency.

We are increasingly utilising platform studies for our early clinical trials that compare multiple potential drugs for a single disease. For example, patients can be enrolled to a platform study in cardiovascular disease based on results of biomarker tests for different sub-types of their specific disease. Depending on the response to the initial treatment, 然后,患者可能会在平台试验中切换到其他药物, as indicated by their disease biomarkers.



By designing patient-centric trials, improving the patient experience, and using digital technology, 澳门第一赌城在线娱乐正在不断扩大澳门第一赌城在线娱乐接触不同患者群体的能力.




为社会和地球的健康提供可持续的临床试验


Improving inclusion and diversity in our clinical trials

澳门第一赌城在线娱乐致力于设计公平的临床项目,从想法的开始到病人的护理. 澳门第一赌城在线娱乐的方法包括增加临床试验参与者的多样性, so trials better reflect the patients who may use our medicines, which ensures we have a robust and reliable body of evidence.



Prioritising diversity in our clinical trials is key to meeting the needs of our patients and of regulators – it is also simply ‘good science’


Reducing the environmental impact of our trials

We focus on running our trials sustainably, to reduce greenhouse gas emissions and environmental impact, helping create a healthy future for society and the planet. We are using a multitude of operational and digital health solutions throughout the clinical trial process – from study design to data analysis. 澳门第一赌城在线娱乐的业务创新包括减少面对面会议和病人的门诊就诊, 通过更好地预测哪里需要实验室试剂盒来减少浪费的数量, 将未使用的工具包转移到其他医疗机构,并减少一次性塑料的使用.





Who could benefit from innovation in clinical trials?

临床试验创新的好处是显著的,可以对整个生态系统产生积极影响. These include:

Our objective is to run our trials more efficiently and get potential new medicines to patients more quickly – through innovation we’re reducing the time commitment for patients and investigators and improving the trial experience to benefit all involved.

Michele Sample VP Clinical Operations, Late-Stage Oncology, AstraZeneca



Latest updates in clinical innovation

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Veeva ID: Z4-56718
Date of preparation: July 2023